Inferring Novel Tumor Suppressor Genes with a Protein-Protein Interaction Network and Network Diffusion Algorithms
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چکیده
منابع مشابه
Inferring Protein Interaction Network by Boosting Algorithm
One of major goals of functional genomics is to elucidate protein interaction networks for whole organisms. Determining protein interactions provides not only detailed functional insights on characterized proteins, but also an information base for identifying biological complexes and metabolic or signal transduction pathways [1]. The recent emergence of high-throughput proteomics techniques has...
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Naturally occurring networks exhibit quantitative features revealing underlying growth mechanisms. Numerous network mechanisms have recently been proposed to reproduce specific properties such as degree distributions or clustering coefficients. We present a method for inferring the mechanism most accurately capturing a given network topology, exploiting discriminative tools from machine learnin...
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Background and objectives: Non-alcoholic fatty liver disease (NAFLD) is a common liver condition. On the other hand, coffee consumption has shown promising for gastrointestinal diseases. Detection of the most valuable biomarkers of decaffeinated coffee treatment in healthy and non-alcoholic fatty liver disease conditions was the aim of the present study. Methods:</stro...
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ژورنال
عنوان ژورنال: Molecular Therapy - Methods & Clinical Development
سال: 2018
ISSN: 2329-0501
DOI: 10.1016/j.omtm.2018.06.007